FMRP Rabbit Monoclonal Antibody (CAB4539)
- SKU:
- CAB4539
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- FMRP
- FRAXA
- POF
- POF1
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | FMRP Rabbit Monoclonal Antibody |
SKU: | CAB4539 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FMRP (Q06787). |
Sequence: | MEEL VVEV RGSN GAFY KAFV KDVH EDSI TVAF ENNW QPDR QIPF HDVR FPPP VGYN KDIN ESDE VEVY SRAN EKEP CCWW LAKV RMIK GEFY VIEY AACD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | POF; FMRP; POF1; FRAXA |
Positive Sample: | SH-SY5Y,Mouse lung,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, nucleolus. |
Calculated MW: | 71kDa |
Observed MW: | 70-80kDa |
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2332 |
Clone Number: | ARC1026 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |