The FMR1NB Polyclonal Antibody (CAB5183) is specifically designed for research involving FMR1NB, a protein encoded by the FMR1 gene and implicated in fragile X syndrome. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot and immunohistochemistry applications.FMR1NB is a crucial protein involved in regulating translation and synaptic plasticity in the brain, making it a key player in neurodevelopment and cognitive function. Dysregulation of FMR1NB has been linked to Fragile X syndrome, the most common form of inherited intellectual disability and autism spectrum disorder.This antibody binds specifically to the FMR1NB protein, allowing for precise detection and analysis in various cell types and tissues.
Its high specificity and sensitivity make it an ideal tool for researchers studying neurodevelopmental disorders, autism, and other conditions related to FMR1 gene dysfunction.Understanding the role of FMR1NB in fragile X syndrome and other neurological disorders is essential for developing targeted therapies and interventions to improve the quality of life for affected individuals. The FMR1NB Polyclonal Antibody (CAB5183) offers researchers a valuable tool for further dissecting the mechanisms underlying these conditions and exploring potential treatment strategies.
Product Name:
FMR1NB Rabbit Polyclonal Antibody
SKU:
CAB5183
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-183 of human FMR1NB (NP_689791.1).
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FMR1NB Antibody (CAB5183) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
