FMO5 Rabbit Polyclonal Antibody (CAB7673)
- SKU:
- CAB7673
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | FMO5 Rabbit Polyclonal Antibody |
SKU: | CAB7673 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human FMO5 (NP_001138302.1). |
Sequence: | MTKK RIAV IGGG VSGL SSIK CCVE EGLE PVCF ERTD DIGG LWRF QENP EEGR ASIY KSVI INTS KEMM CFSD YPIP DHYP NFMH NAQV LEYF RMYA KEFD LLKY IRFK TTVC SVKK QPDF ATSG QWEV VTES EGKK EMNV FDGV MVCT GHHT NAHL PLES FPGI EKFK GQYF HSRD YKNP EGFT GKRV IIIG IGNS GGDL AVEI SQTA KQVF LSTR RGAW ILNR VGDY GYPA DVLF SSRL THFI WKIC GQSL ANKY LEKK INQR FDHE MFGL KPKH RSKD IALT E |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | hBVMO1; FMO5 |
Positive Sample: | Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2330 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |