The FMN2 Polyclonal Antibody (PACO19672) is a valuable tool for researchers investigating FMN2, a protein associated with cell migration and cytoskeletal organization. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blotting applications. By binding specifically to the FMN2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.
FMN2 is known for its role in regulating actin dynamics and promoting cell motility, making it a key player in processes such as cell migration and adhesion. Understanding the function of FMN2 is crucial for elucidating its involvement in cancer metastasis and other cellular processes. By targeting FMN2 with this antibody, researchers can gain valuable insights into the mechanisms by which FMN2 contributes to cellular behavior and disease progression.
Antibody Name:
FMN2 Antibody (PACO19672)
Antibody SKU:
PACO19672
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human FMN2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19672(FMN2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19672(FMN2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.
Synonyms:
formin 2
UniProt Protein Function:
FMN2: Belongs to the formin homology family. Cappuccino subfamilyProtein type: Nucleolus; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 1q43Cellular Component: endoplasmic reticulum membrane; cytoplasmic vesicle membrane; microvillus; perinuclear region of cytoplasm; plasma membrane; nucleolus; spindle; cell cortex; cytosol; actin cytoskeletonMolecular Function: actin bindingBiological Process: oogenesis; vesicle-mediated transport; homologous chromosome movement towards spindle pole during meiosis I; establishment of meiotic spindle localization; protein transport; intracellular transport; multicellular organismal development; polar body extrusion after meiotic divisions; negative regulation of protein catabolic process; response to DNA damage stimulus; negative regulation of apoptosisDisease: Mental Retardation, Autosomal Recessive 47
UniProt Protein Details:
NCBI Summary:
Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.[supplied by OMIM, Apr 2010]
