The FMN2 Polyclonal Antibody (PACO04785) is a valuable tool for researchers studying FMN2, a protein involved in various cellular processes, including cell shape, adhesion, and migration. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. It binds to the FMN2 protein, enabling researchers to detect and analyze its expression in different cell types.FMN2, also known as formin 2, plays a critical role in cytoskeletal organization and dynamics, making it essential for cell migration and invasion. Dysregulation of FMN2 expression has been implicated in diseases such as cancer, where abnormal cell migration and invasion contribute to tumor progression and metastasis.
By studying FMN2, researchers can gain insights into the mechanisms underlying these processes and potentially identify new therapeutic targets for cancer treatment.Overall, the FMN2 Polyclonal Antibody is a valuable tool for scientists investigating the role of FMN2 in various physiological and pathological conditions. Its high specificity and reliability make it a valuable asset for studies in cell biology, cancer research, and other fields where FMN2 is implicated.
Antibody Name:
FMN2 Antibody
Antibody SKU:
PACO04785
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human Formin 2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
FMN2; Formin-2
UniProt Protein Function:
FMN2: Belongs to the formin homology family. Cappuccino subfamilyProtein type: Nucleolus; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 1q43Cellular Component: endoplasmic reticulum membrane; cytoplasmic vesicle membrane; microvillus; perinuclear region of cytoplasm; plasma membrane; nucleolus; spindle; cell cortex; cytosol; actin cytoskeletonMolecular Function: actin bindingBiological Process: oogenesis; vesicle-mediated transport; homologous chromosome movement towards spindle pole during meiosis I; establishment of meiotic spindle localization; protein transport; intracellular transport; multicellular organismal development; polar body extrusion after meiotic divisions; negative regulation of protein catabolic process; response to DNA damage stimulus; negative regulation of apoptosisDisease: Mental Retardation, Autosomal Recessive 47
UniProt Protein Details:
NCBI Summary:
Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.[supplied by OMIM, Apr 2010]
