The FLT4 Polyclonal Antibody (CAB5605) is an essential tool for researchers studying FLT4, a receptor tyrosine kinase involved in lymphangiogenesis and angiogenesis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.FLT4, also known as VEGFR-3, plays a critical role in the development and maintenance of the lymphatic vasculature. Its dysregulation has been implicated in various diseases, including cancer and lymphedema.
By targeting FLT4 with this antibody, researchers can better understand its function and potential therapeutic implications in these contexts.This antibody enables the detection and analysis of FLT4 protein in a variety of cell types, making it ideal for studies in vascular biology, oncology, and lymphatic disorders. By uncovering the mechanisms of FLT4 signaling, researchers can pave the way for novel treatment strategies and targeted therapies.
Product Name:
FLT4 Rabbit Polyclonal Antibody
SKU:
CAB5605
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 330-553 of human VEGFR3/FLT4 (NP_002011.2).
Cell membrane, Cytoplasm, Nucleus, Secreted, Single-pass type I membrane protein.
Calculated MW:
153kDa
Observed MW:
150kDa
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.
Purification Method:
Affinity purification
Gene ID:
2324
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver using VEGFR3/FLT4 Rabbit pAb(CAB5605) at 1:500 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Enhanced Kit (AbGn00021).Exposuretime:60s.
