The FLT4 Polyclonal Antibody (CAB13304) is a valuable tool for researchers studying FLT4, a cell surface receptor involved in lymphatic vessel development and maintenance. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it a reliable choice for Western blot applications. By binding to the FLT4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for immunology and cancer research studies.
FLT4, also known as VEGFR-3, plays a crucial role in lymphangiogenesis and lymphatic endothelial cell function. Its involvement in regulating lymphatic vessel growth and maintenance makes it a key target for research into conditions such as lymphedema, cancer metastasis, and inflammatory disorders. Understanding the function of FLT4 is essential for developing targeted therapies that can modulate lymphatic vessel formation and function in disease settings.
Product Name:
FLT4 Rabbit Polyclonal Antibody
SKU:
CAB13304
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1174-1363 of human VEGFR3/FLT4 (NP_891555.2).
Cell membrane, Cytoplasm, Nucleus, Secreted, Single-pass type I membrane protein.
Calculated MW:
153kDa
Observed MW:
178kDa
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.
Purification Method:
Affinity purification
Gene ID:
2324
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of MCF7 cells using VEGFR3/FLT4 Rabbit pAb (CAB13304) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
