The FLT4 Polyclonal Antibody (CAB12332) is a valuable tool for researchers studying the FLT4 protein, also known as vascular endothelial growth factor receptor 3. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the FLT4 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for research in angiogenesis, lymphangiogenesis, and cancer progression.The FLT4 protein is a key player in the regulation of lymphatic vessel formation and maintenance, as well as in tumor lymphangiogenesis.
Its role in these processes makes it a promising target for therapeutic interventions in conditions such as cancer metastasis and lymphedema. By studying the expression and activity of FLT4 using this polyclonal antibody, researchers can gain valuable insights into the mechanisms underlying these physiological and pathological processes, paving the way for the development of novel treatment strategies.
Product Name:
FLT4 Rabbit Polyclonal Antibody
SKU:
CAB12332
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1230-1329 of human VEGFR3/FLT4 (NP_891555.2).
Cell membrane, Cytoplasm, Nucleus, Secreted, Single-pass type I membrane protein.
Calculated MW:
153kDa
Observed MW:
180kDa
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.
Purification Method:
Affinity purification
Gene ID:
2324
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using VEGFR3/FLT4 Rabbit pAb (CAB12332) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
