VEGFR1 Rabbit Polyclonal Antibody (CAB1277)
- SKU:
- CAB1277
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Description
Product Name: | VEGFR1 Rabbit Polyclonal Antibody |
SKU: | CAB1277 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human VEGFR1 (NP_002010.2). |
Sequence: | LTGS SSGS KLKD PELS LKGT QHIM QAGQ TLHL QCRG EAAH KWSL PEMV SKES ERLS ITKS ACGR NGKQ FCST LTLN TAQA NHTG FYSC KYLA VPTS KKKE TESA IYIF ISDT GRPF VEMY SEIP EIIH MTEG RELV IPCR VTSP NITV TLKK FPLD TLIP DGKR IIWD SRKG FIIS NATY KEIG LLTC EATV NGHL YKTN YLTH RQTN TIID VQIS TPRP VKLL RGHT LVLN CTAT TPLN TRVQ MTWS YPDE KNKR ASVR RRID QSNS HANI FYSV LTID K |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | FLT; FLT-1; VEGFR1; VEGFR-1 |
Positive Sample: | Mouse lung,Mouse kidney,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Endosome, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 151kDa |
Observed MW: | 151kDa |
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Purification Method: | Affinity purification |
Gene ID: | 2321 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |