FLRT2 Rabbit Polyclonal Antibody (CAB17668)
- SKU:
- CAB17668
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | FLRT2 Rabbit Polyclonal Antibody |
SKU: | CAB17668 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1). |
Sequence: | SNLK QLTA RNNP WFCD CSIK WVTE WLKY IPSS LNVR GFMC QGPE QVRG MAVR ELNM NLLS CPTT TPGL PLFT PAPS TASP TTQP PTLS IPNP SRSY TPPT P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FLRT2 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | extracellular exosome, extracellular space, neuron projection, plasma membrane, synapse |
Calculated MW: | 74kDa |
Observed MW: | 80kDa |
This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23768 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |