The FLRT2 Rabbit Polyclonal Antibody (CAB17668) is a crucial tool for researchers studying FLRT2, a transmembrane protein involved in neural development and axon guidance. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to FLRT2, this antibody allows for the detection and analysis of FLRT2 protein in various cell types, making it essential for research in neuroscience and developmental biology.FLRT2 plays a key role in neural circuit formation and synaptic plasticity, making it a critical target for studies related to neurodevelopmental disorders and brain function.
Understanding the function and regulation of FLRT2 is essential for uncovering the mechanisms underlying neural network formation and connectivity. The FLRT2 Rabbit Polyclonal Antibody is an invaluable tool for researchers aiming to elucidate the role of FLRT2 in neurological processes and potential therapeutic interventions.
Product Name:
FLRT2 Rabbit Polyclonal Antibody
SKU:
CAB17668
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1).
This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23768
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using FLRT2 Rabbit pAb (CAB17668) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
