The Flotillin-1 Polyclonal Antibody (CAB6220) is an essential tool for researchers studying the flotillin-1 protein, which is involved in cell signaling, membrane trafficking, and lipid raft organization. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human flotillin-1 samples, making it ideal for Western blot applications.Flotillin-1 is a key player in various cellular processes, including endocytosis, cell adhesion, and signal transduction. Its presence in lipid rafts, specialized membrane microdomains, suggests a role in organizing membrane proteins and facilitating cellular communication.
Research on flotillin-1 is crucial for understanding its impact on cell function and its potential implications in diseases like cancer, neurodegenerative disorders, and metabolic conditions.By utilizing the Flotillin-1 Polyclonal Antibody, researchers can explore the localization, expression, and function of flotillin-1 in different cell types and experimental conditions. This antibody is a valuable tool for investigating the role of flotillin-1 in physiological and pathological processes, offering insights into potential therapeutic targets and strategies for disease intervention.
Product Name:
Flotillin 1 Rabbit Polyclonal Antibody
SKU:
CAB6220
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 155-427 of human Flotillin 1 (NP_005794.1).
This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10211
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and Flotillin 1 knockout (KO) 293T cells, using [KO Validated] Flotillin 1 Rabbit pAb (CAB6220) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
