The Flotillin-1 Polyclonal Antibody is a valuable tool for researchers studying flotillin-1, a key protein involved in membrane microdomain organization and cellular signaling. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, and is validated for use in Western blot applications. By binding to the flotillin-1 protein, researchers can effectively detect and analyze its expression in various cell types, making it an essential reagent for studies in cell biology and signal transduction.
Flotillin-1 is a crucial component of lipid rafts, specialized membrane domains that play a role in signal transduction, vesicular trafficking, and cell adhesion. Its involvement in these processes makes it a target of interest in research on cancer, neurodegenerative diseases, and infectious diseases. Understanding the function of flotillin-1 can provide insights into the mechanisms of disease progression and help in the development of novel therapeutic strategies targeting membrane microdomains.
Product Name:
Flotillin 1 Polyclonal Antibody
SKU:
CAB21832
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 128-427 of human Flotillin 1 (NP_005794.1).
This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10211
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Flotillin 1 Rabbit pAb (CAB21832) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
