FLNC Rabbit Polyclonal Antibody (CAB13018)
- SKU:
- CAB13018
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | FLNC Rabbit Polyclonal Antibody |
SKU: | CAB13018 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2160-2340 of human FLNC (NP_001449.3). |
Sequence: | IPGN WFQM VSAQ ERLT RTFT RSSH TYTR TERT EISK TRGG ETKR EVRV EEST QVGG DPFP AVFG DFLG RERL GSFG SITR QQEG EASS QDMT AQVT SPSG KVEA AEIV EGED SAYS VRFV PQEM GPHT VAVK YRGQ HVPG SPFQ FTVG PLGE GGAH KVRA GGTG LERG VAGV PAEF SIWT R |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | ABPA; ABPL; FLN2; MFM5; MPD4; RCM5; CMH26; ABP-280; ABP280A; FLNC |
Positive Sample: | A-549,LO2,NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane, Peripheral membrane protein, Z line, cytoskeleton, myofibril, sarcomere. |
Calculated MW: | 291kDa |
Observed MW: | 302kDa |
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Mutations in this gene are a cause of cardiopathy. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2318 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |