FLNB Rabbit Polyclonal Antibody (CAB2481)
- SKU:
- CAB2481
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | FLNB Rabbit Polyclonal Antibody |
SKU: | CAB2481 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1686-1785 of human FLNB (NP_001157789.1). |
Sequence: | PDGT EAEA DVIE NEDG TYDI FYTA AKPG TYVI YVRF GGVD IPNS PFTV MATD GEVT AVEE APVN ACPP GFRP WVTE EAYV PVSD MNGL GFKP FDLV IPFA |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 IF/ICC,1:20 - 1:100 |
Synonyms: | AOI; FH1; SCT; TAP; LRS1; TABP; FLN-B; FLN1L; ABP-278; ABP-280; FLNB |
Positive Sample: | HeLa,NIH/3T3,A-431,Mouse liver,Mouse kidney,Mouse uterus,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Z line, cell cortex, cytoskeleton, myofibril, sarcomere. |
Calculated MW: | 278kDa |
Observed MW: | 298kDa |
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2317 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |