FLG Rabbit Polyclonal Antibody (CAB20011)
- SKU:
- CAB20011
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | FLG Rabbit Polyclonal Antibody |
SKU: | CAB20011 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human FLG (NP_002007.1). |
Sequence: | MSTL LENI FAII NLFK QYSK KDKN TDTL SKKE LKEL LEKE FRQI LKNP DDPD MVDV FMDH LDID HNKK IDFT EFLL MVFK LAQA YYES TRKE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | FLG1; ATOD2; FLG-1; FLG |
Positive Sample: | NTERA-2,U2OS,Mouse stomach,Mouse liver,Rat stomach,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasmic ribonucleoprotein granule, cytosol, keratohyalin granule, nucleus |
Calculated MW: | 435kDa |
Observed MW: | 40-100kDa |
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.
Purification Method: | Affinity purification |
Gene ID: | 2312 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |