FKBP51/FKBP5 Rabbit Polyclonal Antibody (CAB3863)
- SKU:
- CAB3863
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | FKBP51/FKBP5 Rabbit Polyclonal Antibody |
SKU: | CAB3863 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 308-457 of human FKBP51/FKBP5 (NP_001139247.1). |
Sequence: | ESKA SESF LLAA FLNL AMCY LKLR EYTK AVEC CDKA LGLD SANE KGLY RRGE AQLL MNEF ESAK GDFE KVLE VNPQ NKAA RLQI SMCQ KKAK EHNE RDRR IYAN MFKK FAEQ DAKE EANK AMGK KTSE GVTN EKGT DSQA MEEE KPEG HV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | P54; AIG6; FKBP51; FKBP54; PPIase; Ptg-10; FKBP51/FKBP5 |
Positive Sample: | MCF7,HT-1080,SH-SY5Y,Jurkat,Mouse liver,Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 51kDa |
Observed MW: | 51kDa |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2289 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |