The FKBP2 Polyclonal Antibody offered by AssayGenie (ABM47302) is a valuable tool for researchers studying FK506-binding protein 2 (FKBP2), a protein involved in various cellular processes such as protein folding, trafficking, and signaling. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for use in Western blot applications.FKBP2 is known to interact with immunosuppressant drugs like FK506 and rapamycin, highlighting its role in immune regulation. Furthermore, FKBP2 has been implicated in the pathogenesis of certain diseases, including cancer and neurodegenerative disorders.
Therefore, understanding the function and regulation of FKBP2 is essential for advancing research and developing targeted therapies for these conditions.By utilizing the FKBP2 Polyclonal Antibody, researchers can accurately detect and analyze FKBP2 protein levels in various cell types, paving the way for insights into its biological functions and potential therapeutic applications. This antibody is a valuable resource for investigations in immunology, cancer biology, and drug discovery, offering new opportunities for advancing scientific knowledge and improving patient outcomes.
Product Name:
FKBP2 Polyclonal Antibody
SKU:
CAB21404
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-142 of human FKBP2 (NP_004461.2).
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
2286
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FKBP2 antibody (CAB21404) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
