The FKBP1B Polyclonal Antibody (CAB9074) is a valuable tool for researchers studying FKBP1B, a protein involved in protein folding and cell signaling pathways. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications.FKBP1B, also known as FK506-binding protein 1B, is known for its role in regulating the activity of proteins involved in cell growth and differentiation. By targeting FKBP1B with this antibody, researchers can detect and analyze its expression levels in various cell types, providing important insights into its function in cellular processes.
The FKBP1B Polyclonal Antibody is particularly useful for studies in cell biology and signal transduction, as well as for investigating the potential role of FKBP1B in diseases such as cancer, neurodegenerative disorders, and immune-related conditions. By understanding the function of FKBP1B, researchers can uncover new therapeutic targets and approaches for treating these diseases.
Product Name:
FKBP1B Rabbit Polyclonal Antibody
SKU:
CAB9074
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_473374.1).
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
2281
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FKBP1B Rabbit pAb (CAB9074) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
