The FKBP1B Polyclonal Antibody (CAB16375) is specifically designed for research involving FK506 binding protein 1B (FKBP1B), a protein known for its role in immunoregulation and protein folding. This antibody, derived from rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding to the FKBP1B protein, researchers can effectively detect and study its expression in various cell types, making it a valuable tool for investigations in immunology, cell biology, and cancer research.FKBP1B is a member of the FK506-binding protein (FKBP) family, known for its involvement in protein folding and in modulating the activity of various proteins, including immune response regulators.
Its significance in immune regulation and cellular processes highlights its potential as a target for studying diseases such as cancer, inflammatory disorders, and autoimmune conditions. By utilizing the FKBP1B Polyclonal Antibody, researchers can gain insights into the function and regulation of FKBP1B, ultimately advancing our understanding of its role in health and disease.
Product Name:
FKBP1B Rabbit Polyclonal Antibody
SKU:
CAB16375
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_473374.1).
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
2281
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FKBP1B Rabbit pAb (CAB16375) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
