The FKBP11 Polyclonal Antibody is a valuable tool for researchers studying FKBP11, a protein involved in cell signaling and protein folding processes. This antibody, generated in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples.FKBP11, also known as FK506-binding protein 11, is a member of the FK506-binding protein family and is involved in regulating the activity of proteins through its chaperone function. Research on FKBP11 has shown its role in various cellular processes, including protein trafficking, proteasomal degradation, and signaling pathways.By using the FKBP11 Polyclonal Antibody, researchers can detect and analyze FKBP11 protein expression in different cell types, making it an ideal tool for studies in molecular biology, cell biology, and drug discovery.
Understanding the function of FKBP11 may provide insights into its potential as a therapeutic target for various diseases, including cancer, neurodegenerative disorders, and autoimmune conditions.Overall, the FKBP11 Polyclonal Antibody offers a reliable and specific tool for investigating the role of FKBP11 in cellular processes and disease pathogenesis, ultimately advancing our understanding of its potential as a therapeutic target.
Product Name:
FKBP11 Polyclonal Antibody
SKU:
CAB23048
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-150 of human FKBP11 (NP_057678.1).
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
FKBP19; FKBP11
Positive Sample:
RPMI 8226,Mouse pancreas,Rat pancreas
Conjugate:
Unconjugated
Calculated MW:
98kDa
Observed MW:
22kDa
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).
Purification Method:
Affinity purification
Gene ID:
51303
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using FKBP11 antibody (CAB23048) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
