The FKBP10 Polyclonal Antibody (CAB12931) is a valuable tool for researchers studying FKBP10, a protein involved in the regulation of collagen biosynthesis and protein folding. This antibody, produced in rabbits, exhibits high specificity for FKBP10 in human samples and is ideal for Western blot applications.FKBP10, also known as FK506-binding protein 65, is a key player in ensuring the proper folding and stability of collagen molecules, which are essential for maintaining the structural integrity of tissues in the body. Dysregulation of FKBP10 has been linked to various diseases related to collagen abnormalities, such as osteogenesis imperfecta and connective tissue disorders.
By targeting FKBP10 with this polyclonal antibody, researchers can investigate the role of this protein in different cell types and tissues, shedding light on its functions in normal physiology and disease pathology. This antibody will be a valuable asset for studies in molecular biology, biochemistry, and medical research focused on understanding the complex mechanisms underlying collagen biology and related disorders.
Product Name:
FKBP10 Rabbit Polyclonal Antibody
SKU:
CAB12931
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 303-582 of human FKBP10 (NP_068758.3).
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
60681
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type(WT) and FKBP10 knockout (KO) HeLa(KO) cells, using [KO Validated] FKBP10 Rabbit pAb (CAB12931) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
