The FITC Anti-Rat CD45RA Antibody (OX-33) offered by Assay Genie is a highly specialized tool for research involving rat CD45RA, a key cell surface marker associated with subsets of immune cells. This antibody, designed specifically for flow cytometry applications, is meticulously validated for its specificity and sensitivity in detecting CD45RA-expressing cells in rat samples.CD45RA, a marker for naïve T cells and regulatory T cells, is crucial for understanding the immune response and its modulation in various physiological and pathological conditions. The OX-33 antibody enables precise detection and characterization of CD45RA-positive cell populations in experimental settings, facilitating in-depth studies in immunology, autoimmune diseases, and transplantation research.
By utilizing the FITC Anti-Rat CD45RA Antibody (OX-33) from Assay Genie, researchers can delve deeper into the functional roles of CD45RA-expressing cells, unraveling their contributions to immune regulation, tolerance, and disease progression. This antibody serves as an indispensable tool for investigating the intricate complexities of the immune system in the context of rat models, offering valuable insights for therapeutic strategies and immunomodulatory interventions.
Product Title:
FITC Anti-Rat CD45RA Antibody [OX-33]
SKU:
AGEL3423
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
OX-33
Synonyms:
Leukocyte common antigen; high molecular weight form;
Host Species:
Mouse
Reactivity:
Rat
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
24699
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets. CD45RA is one of the CD45 isoforms with a molecular weight of 200-220 kD. It is expressed almost exclusively on B cells. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins, including galectin-1, CD2, CD3, and CD4.