The FITC Anti-Rat CD3 Antibody (G4.18) (AGEL2458) offered by AssayGenie is a powerful tool for researchers studying immune responses in rats. Specifically designed to target the CD3 protein found on the surface of rat immune cells, this antibody is essential for analyzing and detecting CD3 expression in various experimental settings.The AGEL2458 antibody is highly reactive with rat samples and is validated for use in flow cytometry and immunofluorescence applications. By binding to the CD3 protein, it allows for precise visualization and investigation of T cell populations in rat models, making it an invaluable resource for understanding the immune system in both health and disease.
CD3 is a crucial component of the T cell receptor complex and plays a central role in T cell activation and function. Studying CD3 expression and regulation is essential for unraveling the complexities of immune responses, making this antibody an indispensable asset for immunologists and researchers exploring topics such as autoimmune diseases, infectious diseases, and immunotherapy.Enhance your research capabilities with the FITC Anti-Rat CD3 Antibody (G4.18) (AGEL2458) from AssayGenie and unlock new insights into the intricate workings of rat immune responses.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P19377 Q64159 D4A5M2
Gene ID:
25710,300678,315609,25300
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3 is a complex composed of δ, γ, ε, and ζ chains. They are 20-25 kD members of the immunoglobulin superfamily and associated with the T cell receptor (TCR). CD3 is expressed on thymocytes, peripheral T cells, some NK-T cells, and dendritic epidermal T cells. CD3 is involved in antigen recognition, signal transduction, and T cell activation.