The FITC Anti-Rat CD3 Antibody (G4.18) is a crucial tool for researchers studying immune responses in rat models. This antibody, available from Assay Genie, specifically targets CD3, a key cell surface marker found on T cells. The FITC-conjugated antibody is highly sensitive and ideal for flow cytometry applications, allowing for precise identification and analysis of T cell populations in experimental settings.CD3 is essential for T cell activation and function, playing a fundamental role in the adaptive immune response. By targeting CD3 with the FITC Anti-Rat CD3 Antibody (G4.18), researchers can investigate T cell activation, proliferation, and differentiation in rat models of various diseases, including autoimmune disorders, infectious diseases, and cancer.
The antibody's high specificity and fluorescence conjugation enable accurate detection and quantification of CD3-expressing T cells, providing valuable insights into immune system dynamics and responses.Overall, the FITC Anti-Rat CD3 Antibody (G4.18) from Assay Genie is a reliable reagent for immunological research, offering a precise and effective tool for studying T cell biology and immune responses in rat models.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P19377 Q64159 D4A5M2
Gene ID:
25710,300678,315609,25300
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3 is a complex composed of δ, γ, ε, and ζ chains. They are 20-25 kD members of the immunoglobulin superfamily and associated with the T cell receptor (TCR). CD3 is expressed on thymocytes, peripheral T cells, some NK-T cells, and dendritic epidermal T cells. CD3 is involved in antigen recognition, signal transduction, and T cell activation.