The FITC Anti-Mouse TCR Antibody (GL3) is a high-quality antibody designed for research involving T cell receptor (TCR) detection in mouse samples. This antibody, labeled with fluorescein isothiocyanate (FITC), allows for easy visualization and analysis of TCR expression in T cells. It is specifically raised against the mouse TCR protein, ensuring precise binding and accurate results in various experimental settings.The GL3 FITC Anti-Mouse TCR Antibody is suitable for flow cytometry, immunofluorescence, and immunohistochemistry applications, enabling researchers to study T cell populations and their responses in different tissues and conditions.
Its high specificity and sensitivity make it a valuable tool for investigating immune responses, T cell activation, and TCR signaling pathways.By using the FITC Anti-Mouse TCR Antibody (GL3), researchers can gain insights into T cell dynamics, immune system function, and the role of TCR interactions in immunity. This antibody is a crucial asset for studies in immunology, infectious diseases, and autoimmune disorders, providing essential data for advancing our understanding of T cell biology and developing targeted therapies in the field of immunotherapy.
Product Title:
FITC Anti-Mouse TCR γ/δ Antibody [GL3]
SKU:
AGEL3299
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
GL3
Synonyms:
T cell receptor γ/δ;
Host Species:
Armenian Hamster
Reactivity:
Human;Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
FITC Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q96E93 O88713
Gene ID:
110066,110067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. γ/δ TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8- although some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation.