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FITC Anti-Mouse Perforin Antibody [S16009A] (AGEL3307)

SKU:
AGEL3307
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
ICFCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
S16009A
Conjugation:
FITC
$239
Frequently bought together:

Description

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FITC Anti-Mouse Perforin Antibody [S16009A]

The FITC Anti-Mouse Perforin Antibody (S16009A-AGEL3307) is a valuable tool for researchers investigating the role of perforin, a key protein involved in immune responses and cytotoxicity. This antibody, specifically designed for use with mouse samples, is conjugated with FITC for easy detection and visualization in various experimental settings.Perforin is a pore-forming protein essential for the function of cytotoxic T cells and natural killer cells in eliminating infected or abnormal cells. By targeting and creating channels in the cell membrane of target cells, perforin facilitates the entry of granzymes, which ultimately induce cell death.

Understanding the mechanisms underlying perforin-mediated cytotoxicity is crucial for elucidating immune responses to infections, cancer surveillance, and autoimmune diseases.The FITC Anti-Mouse Perforin Antibody (S16009A-AGEL3307) offers high specificity and sensitivity in detecting perforin expression, making it an ideal choice for flow cytometry, immunofluorescence, and other immunological assays. Its reliable performance and accurate results make it a valuable asset for researchers in immunology, oncology, and related fields aiming to dissect the intricate pathways involved in immune surveillance and cell-mediated cytotoxicity.

Product Title:FITC Anti-Mouse Perforin Antibody [S16009A]
SKU:AGEL3307
Size:50 Tests, 100 Tests, 200 Tests
Clone No:S16009A
Synonyms:Prf1; Pfp; Pfn; Pfn-1;Cytolysin;Lymphocyte pore-forming protein;
Host Species:Rat
Reactivity:Mouse
Application:ICFCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P10820
Gene ID:18646 
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.

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