The FITC anti-mouse Ly-6G/Ly-6C (GR-1) Antibody (RB6-8C5) from Assay Genie is a powerful tool for researchers studying immune cell populations in mice. This antibody, fluorescein isothiocyanate (FITC)-conjugated for easy detection, specifically targets Ly-6G and Ly-6C antigens commonly expressed on myeloid cells, including neutrophils and inflammatory monocytes.With high specificity and sensitivity, the FITC anti-mouse Ly-6G/Ly-6C (GR-1) Antibody (RB6-8C5) allows for precise identification and quantification of these cell populations in flow cytometry and immunofluorescence experiments.
Its use can aid in understanding the role of myeloid cells in various physiological and pathological processes, from immune responses to inflammatory diseases.Ideal for immunology, inflammation, and infection research, this antibody is a valuable tool in the study of immune cell dynamics and function in mouse models. Trust Assay Genie for reliable and high-quality antibodies for your research needs.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P35461 P0CW03
Gene ID:
546644 ,17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.