The FITC Anti-Mouse H-2 Antibody (M1/42) (AGEL2410) offered by Assay Genie is a vital tool for researchers studying immune responses in mice. This antibody is specifically designed to recognize and bind to the H-2 molecule in mouse samples, enabling precise detection in various cell types. The versatile nature of this antibody makes it ideal for a range of immunological studies, including investigations into antigen presentation, immune cell activation, and transplantation research.The H-2 molecule is a key player in the mouse immune system, governing the recognition of self and non-self antigens. Understanding its role in immune responses is crucial for unraveling mechanisms of immune activation and tolerance.
The FITC Anti-Mouse H-2 Antibody (M1/42) provides researchers with a reliable tool to study H-2 expression and function, ultimately advancing our knowledge of immune regulation in mice.Whether exploring the dynamics of T cell recognition or investigating the impact of genetic variations on immune responses, the FITC Anti-Mouse H-2 Antibody (M1/42) is a valuable reagent for immunologists, microbiologists, and researchers in related fields. Trust Assay Genie's high-quality antibody to support your research endeavors and uncover new insights into the intricacies of the mouse immune system.
Product Title:
FITC Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL2410
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.