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FITC Anti-Mouse CD80 Antibody [16-10A1] (AGEL2778)

SKU:
AGEL2778
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
16-10A1
Conjugation:
FITC
€119 - €189

Description

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FITC Anti-Mouse CD80 Antibody [16-10A1]

The FITC Anti-Mouse CD80 Antibody (16-10A1) offered by AssayGenie is a cutting-edge tool designed for researchers studying the CD80 molecule in mouse models. CD80, also known as B7-1, is a key co-stimulatory molecule involved in immune activation, particularly in T cell activation and regulation. This antibody, labeled with FITC for fluorescent detection, is specifically engineered for compatibility with mouse samples.Raised in specialized mouse models, this antibody is highly selective and shows minimal cross-reactivity, ensuring accurate and reliable results in immunofluorescence and flow cytometry assays. Its binding specificity to CD80 allows for precise detection and quantification of CD80 expression on the surface of cells, facilitating in-depth analysis of immune responses in various experimental settings.

Given the critical role of CD80 in immune regulation and its implications in conditions such as autoimmune diseases and infections, the FITC Anti-Mouse CD80 Antibody (16-10A1) is an indispensable tool for researchers exploring the complexities of the immune system. With its high sensitivity and specificity, this antibody enables detailed investigations into the function and expression patterns of CD80, paving the way for advancements in immunology research and the development of targeted therapeutic strategies.

Product Title:FITC Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL2778
Size:25µg, 100µg
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:FITC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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