The FITC Anti-Mouse CD4 Antibody (Clone: RM4-5) from Assay Genie (AGEL3451) is a premium research reagent designed for the detection and analysis of CD4, a key cell surface marker involved in immune responses. This antibody, optimized for use in flow cytometry and immunofluorescence applications, specifically targets mouse CD4 molecules, offering high sensitivity and specificity in identifying CD4-positive cells in various experimental settings.CD4 is a crucial T-cell co-receptor that plays a pivotal role in immune regulation and response. By targeting CD4, researchers can gain insights into T-cell subsets, immune activation, and immune tolerance mechanisms.
The FITC-conjugated anti-mouse CD4 antibody facilitates accurate identification and quantification of CD4-expressing cells, aiding in the characterization of immune cell populations and the study of immune-mediated diseases, including autoimmune disorders, infectious diseases, and immunodeficiencies.By utilizing the FITC Anti-Mouse CD4 Antibody (Clone: RM4-5) from Assay Genie, researchers can advance their understanding of immune function, immunological disorders, and therapeutic interventions targeting CD4-positive T cells. Trust in this reliable reagent for precise and reproducible results in your immunology research endeavors.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes and a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a co-receptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase lck.