The FITC Anti-Mouse CD4 Antibody (Clone: GK1.5) offered by AssayGenie is a highly specific antibody designed for research involving CD4, a crucial cell surface marker expressed on helper T cells. This antibody, developed for use in flow cytometry and immunofluorescence applications, is particularly well-suited for identifying and analyzing CD4-positive cells in mouse samples.CD4, a glycoprotein involved in immune system regulation, plays a pivotal role in the activation of T cells and coordination of immune responses. The FITC Anti-Mouse CD4 Antibody (Clone: GK1.5) recognizes and binds specifically to the CD4 antigen, allowing for precise detection and quantification of CD4-expressing cells in various experimental settings.
Its high specificity and sensitivity make it an invaluable tool for researchers studying immune regulation, autoimmune diseases, infectious diseases, and immunotherapy.By using this antibody, researchers can gain valuable insights into the behavior and function of CD4-positive T cells, advancing our understanding of immune responses and paving the way for the development of novel therapeutic strategies. Trust in the FITC Anti-Mouse CD4 Antibody (Clone: GK1.5) from AssayGenie to enhance the precision and reliability of your research in immunology, infectious diseases, and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.