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FITC Anti-Mouse CD3ε Antibody [145-2C11] (AGEL2201)

SKU:
AGEL2201
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
145-2C11
Conjugation:
FITC
€79 - €129

Description

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FITC Anti-Mouse CD3ε Antibody [145-2C11]

The FITC anti-mouse CD3 Antibody (145-2C11) offered by AssayGenie is a powerful tool for researchers investigating immune responses in mice. This antibody specifically targets the CD3 protein, a key component of the T cell receptor complex involved in T cell activation. By utilizing the fluorescein isothiocyanate (FITC) conjugation, this antibody enables precise and sensitive detection of CD3 in flow cytometry and immunofluorescence applications.The 145-2C11 antibody is highly specific to mouse CD3, allowing for accurate identification and analysis of T cells in experimental systems.

This antibody has been rigorously validated for its performance in various assays, ensuring reliable and reproducible results for researchers studying immune function, infection, autoimmunity, and other related fields.By utilizing the FITC anti-mouse CD3 Antibody (145-2C11) from AssayGenie, researchers can delve deeper into the intricate mechanisms of T cell activation and function in mouse models, ultimately advancing our understanding of immune responses and paving the way for the development of novel treatments for a variety of immune-related diseases.

Product Title:FITC Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL2201
Size:25µg, 100µg
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:FITC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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