The FITC Anti-Mouse CD107a Antibody (1D4B) from Assay Genie is a cutting-edge tool for researchers studying immune responses in mouse models. This high-quality antibody specifically targets CD107a, a cell surface marker associated with cytotoxic T cells and natural killer cells.The FITC Anti-Mouse CD107a Antibody (1D4B) is rigorously tested and validated for various applications, including flow cytometry and immunofluorescence. Its fluorescent tag allows for easy and sensitive detection of CD107a expression in different cell populations, providing valuable insights into immune cell activity and function.
Researchers in the fields of immunology, cancer biology, and infectious diseases will benefit from the precision and sensitivity of this antibody in their experiments. By accurately detecting and quantifying CD107a expression, researchers can enhance their understanding of immune responses and develop targeted therapies for various diseases.
Product Title:
FITC Anti-Mouse CD107a Antibody [1D4B]
SKU:
AGEL3286
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
1D4B
Synonyms:
LAMP-1;Lysosome-associated membrane glycoprotein 1; lysosomal membrane glycoprotein 1; CD107 antigen-like family member A; lysosome-associated membrane protein 1;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P11438
Gene ID:
16783
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.