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FITC Anti-Human/Mouse KLRG-1 Antibody [2F1] (AGEL3130)

SKU:
AGEL3130
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Syrian Hamster
Isotype:
Syrian Hamster IgG
Clone:
2F1
Conjugation:
FITC
€159 - €289

Description

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FITC Anti-Human/Mouse KLRG-1 Antibody [2F1]

The FITC Anti-Human Mouse KLRG-1 Antibody (2F1) is a cutting-edge tool designed for researchers studying immune cell populations and immune responses. This high-quality antibody, available from AssayGenie, specifically targets the KLRG-1 protein found on human and mouse cells, making it a versatile option for a range of experiments.KLRG-1, also known as killer cell lectin-like receptor subfamily G member 1, is a cell surface marker associated with immune cell differentiation and function. By using the FITC Anti-Human Mouse KLRG-1 Antibody (2F1), researchers can accurately detect and analyze KLRG-1 expression in different cell types, providing insights into immune cell activation, proliferation, and differentiation processes.

This antibody is suitable for various applications, including flow cytometry and immunofluorescence assays, allowing for detailed examination of KLRG-1 expression patterns in biological samples. Its reliability and specificity guarantee accurate and reproducible results, making it a valuable asset for studies in immunology, cancer research, and other fields where understanding immune cell behavior is crucial.In summary, the FITC Anti-Human Mouse KLRG-1 Antibody (2F1) from AssayGenie is a powerful research tool that enables precise detection and analysis of KLRG-1 expression, facilitating deeper insights into immune cell biology and function.

Product Title:FITC Anti-Human/Mouse KLRG-1 Antibody [2F1]
SKU:AGEL3130
Size:25µg, 100µg
Clone No:2F1
Synonyms:MAFA; 2F1-Ag;
Host Species:Syrian Hamster
Reactivity:Human;Mouse
Application:FCM
Isotype:Syrian Hamster IgG
Isotype Control:FITC Syrian Hamster IgG Isotype Control[SHG-1]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q96E93 O88713
Gene ID:10219,50928
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG20 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

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