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FITC Anti-Human CD8a Antibody [HIT8a] (AGEL3391)

SKU:
AGEL3391
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
HIT8a
Conjugation:
FITC
€89 - €279

Description

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FITC Anti-Human CD8a Antibody [HIT8a]

The FITC Anti-Human CD8a Antibody (HIT8a) is a vital tool for researchers studying the CD8a cell surface molecule, a marker of cytotoxic T cells essential in immune responses. This antibody, produced specifically for use with human samples, is conjugated with FITC for fluorescence detection applications, such as flow cytometry and immunofluorescence.The HIT8a antibody binds specifically to the CD8a protein, enabling precise detection and analysis of CD8a-expressing cells in various biological samples. With its high specificity and sensitivity, this antibody is an invaluable asset for studies in immunology, infectious diseases, and cancer research, where CD8a-positive T cells play crucial roles in immune surveillance and anti-tumor immunity.

By targeting the CD8a molecule with the FITC Anti-Human CD8a Antibody (HIT8a), researchers can gain deeper insights into T cell-mediated immune responses, identify subsets of CD8a-expressing cells, and investigate their functions in health and disease. This antibody offers reliable results and reproducibility, making it a trusted tool for advancing our understanding of immune cell biology and developing innovative therapeutic strategies.

Product Title:FITC Anti-Human CD8a Antibody [HIT8a]
SKU:AGEL3391
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIT8a
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T8;Leu2;MAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01732
Gene ID:925
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

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