The FITC Anti-Human CD81 Antibody (1.3.3.22) offered by Assay Genie is a cutting-edge tool for researchers interested in studying CD81, a key cell surface protein associated with various cellular processes. This antibody, optimized for use in fluorescence-based assays, is engineered for exceptional specificity and sensitivity in detecting human CD81.CD81, a member of the tetraspanin family, plays a pivotal role in cell signaling, membrane organization, and cell fusion events. Its involvement in processes such as T cell activation, viral infection, and intracellular trafficking highlights its significance in both physiological and pathological conditions. The FITC Anti-Human CD81 Antibody (1.3.3.22) provides researchers with a reliable means to investigate the expression and localization of CD81 in different cell types and experimental settings.
With its fluorescent properties, this antibody allows for visually striking visualization of CD81 in flow cytometry, immunofluorescence, and microscopy applications. By targeting CD81 with high specificity, researchers can gain valuable insights into its function and interactions within cellular networks. Additionally, the use of this antibody opens up new avenues for exploring the role of CD81 in diseases such as viral infections, cancer, and immune disorders.Choose the FITC Anti-Human CD81 Antibody (1.3.3.22) from Assay Genie to advance your research efforts and unlock the mysteries of CD81 biology.
Product Title:
FITC Anti-Human CD81 Antibody [1.3.3.22]
SKU:
AGEL2836
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
1.3.3.22
Synonyms:
CD81 antigen;CD81;26 kDa cell surface protein TAPA-1;Target of the antiproliferative antibody 1.Tetraspanin-28;Tspan-28;APA1; TSPAN28;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P60033
Gene ID:
975
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.