The FITC Anti-Human CD73 Antibody (AD2) is a cutting-edge tool in the field of immunology, specifically designed for researchers investigating CD73, a crucial cell surface enzyme known for its role in immune regulation and inflammation. This antibody, meticulously developed and optimized by Assay Genie, offers exceptional reactivity with human samples, ensuring reliable and consistent results in a variety of experimental applications.CD73, a key player in purinergic signaling pathways, is involved in immune responses, cell adhesion, and angiogenesis. By targeting the CD73 protein, this antibody enables precise detection and analysis of CD73 expression in diverse cell types, facilitating detailed insights into its functions and interactions in immunological processes.
Its compatibility with immunofluorescence and flow cytometry techniques further enhances its utility in elucidating the complex mechanisms involving CD73.Researchers studying cancer immunotherapy, autoimmune diseases, and inflammatory conditions will find the FITC Anti-Human CD73 Antibody (AD2) indispensable in their investigations. By deepening the understanding of CD73-mediated signaling pathways and its impact on immune modulation, this antibody paves the way for the development of novel therapeutic strategies targeting CD73 in various disease contexts. Stay at the forefront of immunological research with the precise and reliable detection capabilities of the FITC Anti-Human CD73 Antibody (AD2) from Assay Genie.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P21589
Gene ID:
4907
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD73 is a 70 kD glycophosphatidylinositol (GPI)-linked 5'-nucleotidase, which is also known as ecto-5'-nucleotidase. It converts adenosine monophosphate (AMP) to adenosine. CD73 is expressed on subsets of T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells. It has been reported that CD73 costimulates T cell activation, and mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells.