The FITC Anti-Human CD56 Antibody (B-A19) from Assay Genie is a valuable tool for researchers studying CD56, a cell surface marker commonly utilized in identifying natural killer (NK) cells and neural cell adhesion. This monoclonal antibody, specifically designed for use with human samples, is conjugated with FITC for fluorescent detection, making it suitable for flow cytometry and immunofluorescence applications.CD56, also known as neural cell adhesion molecule (NCAM), is involved in cell adhesion and signaling processes, playing a crucial role in immune responses and nervous system development. Its expression is often used to characterize and study NK cell populations, making this antibody a key component in immunology research focused on understanding the function and behavior of NK cells in various physiological and pathological conditions.
With its high specificity and sensitivity, the FITC Anti-Human CD56 Antibody (B-A19) offers researchers a reliable tool for investigating NK cell biology, immune responses, and neurological disorders. By enabling precise detection and analysis of CD56-expressing cells, this antibody facilitates in-depth exploration of the roles and mechanisms associated with these cell populations, contributing to advancements in immunotherapy, cancer research, and neuroscience.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P51677
Gene ID:
4684
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD56 is a single transmembrane glycoprotein also known as NCAM (neural cell adhesion molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK and NKT cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparan sulfate.