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FITC Anti-Human CD49d Antibody [HP1/2] (AGEL3480)

SKU:
AGEL3480
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2a, k
Clone:
HP1/2
Conjugation:
FITC
€209 - €709
Frequently bought together:

Description

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FITC Anti-Human CD49d Antibody [HP1/2]

The FITC Anti-Human CD49d Antibody (HP1/2) offered by Assay Genie is a valuable tool for researchers studying cell adhesion and migration processes. This antibody specifically targets the CD49d protein, a key integrin involved in cell-extracellular matrix interactions. With its high specificity and sensitivity, this FITC-conjugated antibody allows for precise detection and visualization of CD49d in human samples using fluorescence microscopy or flow cytometry techniques. Its reliability and performance have been validated in various research applications, making it a versatile tool for investigating cell adhesion mechanisms in both normal and pathological conditions.

Researchers in immunology, oncology, and cell biology can benefit from the accurate and reproducible results obtained with the FITC Anti-Human CD49d Antibody (HP1/2). By unraveling the roles of CD49d in cellular processes, this antibody supports the advancement of knowledge in fields such as cancer metastasis, immune cell trafficking, and inflammatory responses. Enhance your research capabilities with this high-quality antibody from Assay Genie.

Product Title:FITC Anti-Human CD49d Antibody [HP1/2]
SKU:AGEL3480
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HP1/2
Synonyms:VLA-4 α chain; α4 integrin; Integrin α4 chain; ITGA4;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P13612
Gene ID:3676
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

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