The FITC Anti-Human CD44 Antibody (HERMES-1) is a versatile tool for researchers studying the CD44 cell surface glycoprotein, a key player in cell adhesion, migration, and signaling processes. This antibody, conjugated with FITC for easy fluorescent detection, is specifically designed for use in flow cytometry and immunofluorescence applications with human samples. CD44 is a multifunctional molecule involved in various physiological and pathological processes, including cancer metastasis, inflammation, and stem cell function. The HERMES-1 antibody recognizes CD44, allowing for precise identification and analysis of CD44-expressing cell populations.
Its high specificity and sensitivity make it a valuable asset in investigating the role of CD44 in different cellular contexts.Researchers in the fields of oncology, immunology, and stem cell biology can leverage the FITC Anti-Human CD44 Antibody (HERMES-1) to deepen their understanding of CD44 biology and its implications in health and disease. By enabling accurate visualization and quantification of CD44 expression, this antibody facilitates detailed studies that contribute to advancing knowledge in various research areas.
Product Title:
FITC Anti-Human CD44 Antibody [Hermes-1]
SKU:
AGEL2406
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
Hermes-1
Synonyms:
LHR;PGP-I;CDw44;Epican;HUTCH-I;
Host Species:
Rat
Reactivity:
Human
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16070
Gene ID:
960
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.