The FITC Anti-Human CD40 Antibody (G28-5) offered by AssayGenie is a cutting-edge tool for researchers delving into immune responses and cell signaling pathways involving CD40. This monoclonal antibody, meticulously crafted for specificity and sensitivity, interacts with human CD40 protein, a key player in immune cell communication and activation.With its fluorescent properties, this antibody is a versatile choice for fluorescence microscopy and flow cytometry studies, allowing for precise visualization and quantification of CD40 expression on various cell types. Its exceptional reactivity and reliability make it a valuable asset in research focused on immunology, autoimmunity, and infectious diseases.
By targeting CD40, a crucial mediator in immune system regulation and inflammation, researchers can gain insights into the intricate mechanisms of immune responses and potential therapeutic interventions. The FITC Anti-Human CD40 Antibody (G28-5) is an indispensable tool for unraveling the complexities of immune modulation and holds immense promise for advancing our understanding of immune-related disorders and therapeutic strategies.
Product Title:
FITC Anti-Human CD40 Antibody [G28.5]
SKU:
AGEL2403
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
G28.5
Synonyms:
Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P25942
Gene ID:
958
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).