The FITC Anti-Human CD34 Antibody (4H11) offered by Assay Genie is a valuable tool for researchers studying CD34, a cell surface marker commonly found on hematopoietic stem cells and endothelial progenitor cells. This antibody is specifically designed for use in flow cytometry applications, enabling the precise detection and analysis of CD34-expressing cells in human samples.CD34 is an important marker in hematopoiesis and vascular biology, playing a key role in cell adhesion, migration, and differentiation. Its expression pattern is crucial for identifying and isolating stem and progenitor cells, making it a vital component in studies related to stem cell research, cancer biology, and regenerative medicine.The FITC Anti-Human CD34 Antibody (4H11) demonstrates high specificity and sensitivity, allowing for accurate identification of CD34-positive cells in complex cell populations.
Its reliable performance makes it an essential tool for researchers interested in characterizing and quantifying CD34-expressing cells in various tissues and experimental models.Overall, the FITC Anti-Human CD34 Antibody (4H11) from Assay Genie is a valuable resource for researchers looking to explore the roles of CD34 in hematopoiesis, vascular biology, and other related fields. Its compatibility with flow cytometry techniques ensures precise and reliable results, facilitating in-depth investigations into the function and regulation of CD34-expressing cells in health and disease.
Product Title:
FITC Anti-Human CD34 Antibody [4H11]
SKU:
AGEL3439
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
4H11
Synonyms:
Gp105-120; My10;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P28906
Gene ID:
947
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.