The FITC Anti-Human CD33 Antibody (6C5) available at www.assaygenie.com/fitc-anti-human-cd33-antibody-6c5/ is a valuable tool for researchers studying CD33, a cell surface protein commonly found on myeloid cells and implicated in various immune functions. This antibody, conjugated with FITC for fluorescent detection, is specifically designed for use in flow cytometry applications involving human samples.CD33 is a transmembrane receptor that plays a crucial role in immune response regulation and is particularly relevant in the context of myeloid cell biology. By targeting CD33, researchers can gain insights into its role in immune cell function and its potential as a therapeutic target in conditions such as leukemia and other hematologic malignancies.
The FITC Anti-Human CD33 Antibody (6C5) provides high specificity and sensitivity in detecting CD33 expression on cell surfaces, making it an ideal tool for immunophenotyping studies and therapeutic target identification. With its validated performance and compatibility with flow cytometry techniques, this antibody is essential for advancing research in immunology, hematology, and cancer biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P20138
Gene ID:
945
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD33 is a 67 kD type I transmembrane glycoprotein also known as Siglec-3, gp67, and p67. It is a sialoadhesion immunoglobulin superfamily member expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes and hematopoietic stem cells. CD33 functions as a sialic acid-dependent cell adhesion molecule with carbohydrate/lectin binding activity.