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FITC Anti-Human CD206 Antibody [15-2] (AGEL3349)

SKU:
AGEL3349
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
44972
Conjugation:
FITC
€189 - €629
Frequently bought together:

Description

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FITC Anti-Human CD206 Antibody [15-2]

The FITC Anti-Human CD206 Antibody (15-2) from AssayGenie is a crucial tool for researchers studying CD206, a key cell surface marker involved in immune responses and inflammatory processes. This antibody, specifically designed for human samples, is highly specific and validated for use in a variety of applications, including flow cytometry, immunofluorescence, and immunohistochemistry.CD206, also known as mannose receptor, is a C-type lectin receptor expressed on macrophages and dendritic cells, playing a pivotal role in antigen presentation and phagocytosis. Its involvement in immune modulation and inflammatory responses makes it an attractive target for investigating diseases such as infectious diseases, cancer, and autoimmune disorders.

The FITC Anti-Human CD206 Antibody (15-2) allows for precise detection and analysis of CD206 expression in different cell types, providing valuable insights into immune-related processes.Researchers in immunology, oncology, and infectious diseases will find the FITC Anti-Human CD206 Antibody (15-2) to be a reliable tool for their studies, enabling detailed exploration of CD206 function and its impact on immune regulation. With its high specificity and sensitivity, this antibody is an essential asset for advancing research in understanding the complex mechanisms of immune responses and the development of targeted therapies.

Product Title:FITC Anti-Human CD206 Antibody [15-2]
SKU:AGEL3349
Size:20 Tests, 100 Tests, 200 Tests
Clone No:15-2
Synonyms:CLEC13D;CLEC13DL;MRC1L1;MMR;hMR;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P22897
Gene ID:4360
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.

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