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FITC Anti-Human CD16 Antibody [3G8] (AGEL2477)

SKU:
AGEL2477
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
3G8
Conjugation:
FITC
$227 - $755
Frequently bought together:

Description

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FITC Anti-Human CD16 Antibody [3G8]

The FITC Anti-Human CD16 Antibody (3G8) offered by Assay Genie is a valuable tool for researchers studying CD16, a significant cell surface molecule involved in immune responses. This monoclonal antibody, specifically designed to target human CD16, is ideal for use in flow cytometry and immunofluorescence applications.CD16, also known as Fc gamma receptor III (FcγRIII), plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC) and phagocytosis. By binding to CD16, this antibody enables the detection and analysis of CD16 expression in various cell types, aiding in the understanding of immune cell function and interactions.

With its high specificity and sensitivity, the FITC Anti-Human CD16 Antibody (3G8) is a reliable tool for researchers exploring immune cell signaling pathways, cell-mediated immune responses, and immunotherapy development. Its application extends to studies in immunology, oncology, and infectious diseases, providing valuable insights into the role of CD16 in immune regulation and disease pathogenesis.

Product Title:FITC Anti-Human CD16 Antibody [3G8]
SKU:AGEL2477
Size:20 Tests, 100 Tests, 200 Tests
Clone No:3G8
Synonyms:FcγRIII;Fc gamma receptor;Fc gamma receptor 3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08637 O75015
Gene ID:941
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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