The FITC Anti-Human CD122 (IL-2RB) Antibody (TU27) is a valuable tool for researchers studying the CD122 receptor, also known as IL-2RB, which is a crucial component in the IL-2 receptor complex involved in immune responses. This antibody, manufactured by Assay Genie, is specifically designed for use in fluorescence-based assays and flow cytometry experiments to detect and analyze the CD122 protein in human samples.The CD122 receptor plays a key role in regulating the proliferation and activation of immune cells, particularly T cells, and is essential for immune surveillance and response to pathogens. By targeting CD122, researchers can gain insights into the mechanisms underlying immune system function and dysfunction, paving the way for the development of novel immunotherapies and treatments for diseases such as cancer, autoimmune disorders, and inflammatory conditions.
With its high specificity and reactivity in human samples, the FITC Anti-Human CD122 (IL-2RB) Antibody (TU27) provides a reliable tool for investigating the role of CD122 in various biological processes and pathological conditions. Whether used in basic research or therapeutic development, this antibody offers a valuable means of advancing our understanding of immune regulation and disease pathology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P14784
Gene ID:
3560
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation.
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