The TTC11 Rabbit Monoclonal Antibody (CAB19666) is a powerful tool for research involving TTC11, a protein associated with mitochondrial metabolism and function. This high-quality antibody, generated in rabbits, exhibits strong reactivity with human samples and has been rigorously validated for Western blot applications. By specifically binding to TTC11, this antibody enables precise detection and analysis of the protein in a variety of cell types, making it an ideal choice for studies in mitochondrial biology, metabolism, and related diseases.
TTC11 plays a key role in maintaining mitochondrial homeostasis and function, making it a promising target for research into metabolic disorders, neurodegenerative diseases, and aging-related conditions. Understanding the functions and regulation of TTC11 is essential for unraveling the complex mechanisms underlying mitochondrial dysfunction in various pathological conditions. The TTC11 Rabbit Monoclonal Antibody provides researchers with a reliable tool to advance their investigations in these critical areas of biomedical research.
Enables identical protein binding activity. Involved in several processes, including calcium-mediated signaling using intracellular calcium source; cellular calcium ion homeostasis; and mitochondrion organization. Acts upstream of or within mitochondrion morphogenesis. Located in mitochondrion and peroxisome. Is integral component of mitochondrial outer membrane and integral component of peroxisomal membrane. Part of protein-containing complex. Biomarker of Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
51024
Clone Number:
ARC5010-03
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and TTC11/FIS1 knockout (KO) HeLa(KO) cells, using [KO Validated] TTC11/FIS1 Rabbit mAb (CAB19666) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
