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FIS1 Monoclonal Antibody [PAT3B7AT] (CPAB0686)

SKU:
CPAB0686
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT3B7AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

FIS1 Monoclonal Antibody [PAT3B7AT] (CPAB0686)

The FIS1 Polyclonal Antibody (CPAB0686) is a valuable tool for researchers studying FIS1, a protein involved in mitochondrial fission and fusion processes. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in a variety of research applications.FIS1 plays a crucial role in mitochondrial dynamics by recruiting fission machinery to the mitochondria, thereby regulating the division of these organelles. Dysregulation of FIS1 has been linked to various diseases, including neurodegenerative disorders and cancer, making it a target of interest for researchers in these fields.

With its high reactivity and specificity, the FIS1 Polyclonal Antibody enables researchers to detect and analyze FIS1 protein expression in different cell types, facilitating a better understanding of its function in mitochondrial dynamics. This antibody is validated for use in Western blot applications, providing reliable and accurate results for studies focusing on mitochondrial biology and related diseases.

Product Name:FIS1 Antibody
Product Sku:CPAB0686
Size:5μg
Host Species:Mouse
Immunogen:Anti-human FIS1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FIS1 protein 1-122 amino acids purified from Ecoli.
Clone:PAT3B7AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:FIS1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 induces cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. FIS1 participates in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission.
Synonyms:TTC11, Tetratricopeptide repeat domain 11, Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae).
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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