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FCN1 Rabbit Polyclonal Antibody (CAB6587)

SKU:
CAB6587
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 2 Anti-FCN1 Antibody CAB6587
  • Immunology Antibodies 2 Anti-FCN1 Antibody CAB6587
  • Immunology Antibodies 2 Anti-FCN1 Antibody CAB6587
  • Immunology Antibodies 2 Anti-FCN1 Antibody CAB6587
$167 - $503
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Description

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Product Name:FCN1 Rabbit Polyclonal Antibody
SKU:CAB6587
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-326 of human FCN1 (NP_001994.2).
Sequence:ADTC PEVK VVGL EGSD KLTI LRGC PGLP GAPG PKGE AGVI GERG ERGL PGAP GKAG PVGP KGDR GEKG MRGE KGDA GQSQ SCAT GPRN CKDL LDRG YFLS GWHT IYLP DCRP LTVL CDMD TDGG GWTV FQRR MDGS VDFY RDWA AYKQ GFGS QLGE FWLG NDNI HALT AQGS SELR VDLV DFEG NHQF AKYK SFKV ADEA EKYK LVLG AFVG GSAG NSLT GHNN NFFS TKDQ DNDV SSSN CAEK FQGA WWYA DCHA SNLN GLYL MGPH ESYA NGIN WSAA KGYK YSYK VSEM KVRP A
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:FCNM; FCN1
Positive Sample:U-937,U-251MG,HepG2,Mouse liver,Mouse heart,Rat liver
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Extracellular side, Peripheral membrane protein, Secreted.
Calculated MW:35kDa
Observed MW:38kDa

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.

Purification Method:Affinity purification
Gene ID:2219
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using FCN1 antibody (CAB6587) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.

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